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Tobias Deuse, M.D.

Tobias Deuse, M.D.

Associate Professor of Surgery
Division of Adult Cardiothoracic Surgery
The Julien I.E. Hoffman, M.D. Endowed Chair in Cardiac Surgery
Director, Minimally-invasive Cardiac Surgery
Surgical Director, Transcatheter Valve Program

Contact Information

Academic Office
500 Parnassus Ave., MUW-405
San Francisco, CA 94143-0118
(415) 353 8890
Tobias.Deuse@ucsf.edu

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  • University of Stuttgart (Germany), BS, Physics, 1994
  • University of Leipzig (Germany) Medical School, 1995
  • Julius-Maximilian-University Würzburg (Germany) Medical School, MD, 2000
  • Ludwig-Maximilian-University Munich (Germany) Medical School, 2001
  • University Hospital Munich-Grosshadern (Germany), Cardiac Surgery, 2001
  • University Heart Center Hamburg-Eppendorf (Germany), Cardiovascular Surgery, 2002-2007
  • Stanford University, Lung and Heart-Lung Transplantation, Fellowship Program, 2007-2009
  • UCSF Heart & Vascular Center
  • Acute Aortic Dissection Repair
  • Aortic Valve Repair & Replacement
  • Arrhythmia
  • Coronary Artery Bypass Grafting (CABG)
  • Heart Transplantation
  • Lung Transplantation
  • Minimally Invasive Atrial Septal Defect (ASD) Closure
  • Minimally Invasive Mitral Valve Surgery
  • Off-Pump Coronary Artery Bypass (OPCAB)
  • Ventricular Aneurysm
  • Ventricular Assist Devices (VAD)
  • Oxidative Stress and Apoptosis
  • Pulmonary Hypertension
  • Stem Cell Immunobiology
  • Transplant Immunology
  • Vascular Biology
  • German

Tobias Deuse, M.D. is a cardiac and heart transplant surgeon internationally renowned for his pioneering work in the development of minimally-invasive techniques for mitral valve repair. 

Dr. Deuse graduated the University of Stuttgart (Germany) in 1994 with a BS in Physics, and in 2000 earned an M.D. from University of Wuerzburg. Dr. Deuse thereafter received advanced training in cardiothoracic surgery at the University Hospital Munich-Grosshadern and University Heart Center Hamburg-Eppendorf. After obtaining his board certification in Germany in 2007 as a heart surgeon, Dr. Deuse completed a surgical fellowship in Lung and Heart-Lung Transplantation at Stanford.

After returning to Germany in 2009, Dr. Deuse was appointed Director for Heart and Lung Transplantation at the University Heart Center in Hamburg. He achieved international acclaim for his development of innovative approaches to heart failure surgery, most notably minimally-invasive techniques for the implantation of ventricular assist systems. 

Dr. Deuse also demonstrated that high success rates could be achieved in mitral valve repair utilizing robotic-assisted (fully) endoscopic surgery. This minimally invasive procedure, also known as "keyhole surgery", has numerous benefits for the patient including substantially reduced post-surgical pain, shorter hospital stays, and a faster recovery and return to normal activities. 

Dr. Deuse has also been the recipient of numerous honors including election to the Board of Directors of the International Society for Heart and Lung Transplantation (ISHLT).

Dr. Deuse's research is focused on vascular biology and pathophysiology. His group was the among the first to elucdiate the novel pathways involved in the development of vascular intimal hyperplasia. Myointimal hyperplasia is a pathological process of the vascular system characterized by abnormal proliferation of smooth muscle cells of the vascular wall that leads to luminal obliteration and subsequent ischemia.

Myointimal hyperplasia may occur in patients after vessel injury during medical procedures (e.g. after balloon dilation or stent placement) or after pathological injury of the blood vessel (e.g. due to inflammation or toxic exposure). It can cause bypass graft failure and in-stent restenosis. To help prevent this and increase the success of treatments for vascular disease including coronary heart disease, his research group is working on the development of new preventive drug regimes and strategies.

Most recent publications from a total of 96
  1. Smits JM, Nossent G, Evrard P, Lang G, Knoop C, Kwakkel-van Erp JM, Langer F, Schramm R, van de Graaf E, Vos R, Verleden G, Rondelet B, Hoefer D, Hoek R, Hoetzenecker K, Deuse T, Strelniece A, Green D, de Vries E, Samuel U, Laufer G, Buhl R, Witt C, Gottlieb J. Lung allocation score: the Eurotransplant model versus the revised US model - a cross-sectional study. Transpl Int. 2018 Apr 17. View in PubMed
  2. Warnecke G, Van Raemdonck D, Smith MA, Massard G, Kukreja J, Rea F, Loor G, De Robertis F, Nagendran J, Dhital KK, Moradiellos Díez FJ, Knosalla C, Bermudez CA, Tsui S, McCurry K, Wang IW, Deuse T, Lesèche G, Thomas P, Tudorache I, Kühn C, Avsar M, Wiegmann B, Sommer W, Neyrinck A, Schiavon M, Calebrese F, Santelmo N, Olland A, Falcoz PE, Simon AR, Varela A, Madsen JC, Hertz M, Haverich A, Ardehali A. Normothermic ex-vivo preservation with the portable Organ Care System Lung device for bilateral lung transplantation (INSPIRE): a randomised, open-label, non-inferiority, phase 3 study. Lancet Respir Med. 2018 05; 6(5):357-367. View in PubMed
  3. Marcus SG, Mahadevan VS, Deuse T. Hybrid Open Minimally-Invasive Transcatheter Mitral Valve Replacement. Ann Thorac Surg. 2018 Mar 29. View in PubMed
  4. Tediashvili G, Wang D, Reichenspurner H, Deuse T, Schrepfer S. Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta. J Vis Exp. 2018 Feb 07; (132). View in PubMed
  5. Sanchez JM, Al-Dosari G, Chu S, Beygui R, Deuse T, Badhwar N, Lee RJ. Hybrid and surgical procedures for the treatment of persistent and longstanding persistent atrial fibrillation. Expert Rev Cardiovasc Ther. 2018 Feb; 16(2):91-97. View in PubMed
  6. Schaefer A, Reichart D, Bernhardt AM, Kubik M, Barten MJ, Wagner FM, Reichenspurner H, Philipp SA, Deuse T. Outcomes of Minimally Invasive Temporary Right Ventricular Assist Device Support for Acute Right Ventricular Failure During Minimally Invasive Left Ventricular Assist Device Implantation. ASAIO J. 2017 Sep/Oct; 63(5):546-550. View in PubMed
  7. Miller KK, Wang D, Hu X, Hua X, Deuse T, Neofytou E, Renne T, Velden J, Reichenspurner H, Schrepfer S, Bernstein D. Thalidomide treatment prevents chronic graft rejection after aortic transplantation in rats - an experimental study. Transpl Int. 2017 Nov; 30(11):1181-1189. View in PubMed
  8. Mitsutake Y, Reifart J, Pyun WB, Lyons JK, Deuse T, Schrepfer S, Ikeno F. Differences in Vascular Response between Balloon Overstretch and Stent Overexpansion in Nonatherosclerotic Porcine Coronary Arteries. Comp Med. 2017 Aug 01; 67(4):350-355. View in PubMed
  9. Magnussen C, Bernhardt AM, Ojeda FM, Wagner FM, Gummert J, de By TMMH, Krabatsch T, Mohacsi P, Rybczynski M, Knappe D, Sill B, Deuse T, Blankenberg S, Schnabel RB, Reichenspurner H. Gender differences and outcomes in left ventricular assist device support: The European Registry for Patients with Mechanical Circulatory Support. J Heart Lung Transplant. 2018 Jan; 37(1):61-70. View in PubMed
  10. Bernhardt AM, Pamirsad MA, Brand C, Reichart D, Tienken M, Barten MJ, Schaefer A, Grahn H, Rybczynski M, Deuse T, Reichenspurner H, Wagner FM. The value of fluorine-18 deoxyglucose positron emission tomography scans in patients with ventricular assist device specific infections†. Eur J Cardiothorac Surg. 2017 Jun 01; 51(6):1072-1077. View in PubMed
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Please note: UCSF Profiles publications are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact CTSI for help.

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